The Oral-Systemic Connection & the Future of Diagnostics

Oral Health = Whole-Body Wellness

Oral health is more than a smile—it’s the foundation of whole-body wellness

Oral pathogens, once believed to be limited to causing gum disease, periodontitis, and peri-implant complications— are now increasingly supported by research as being linked to serious systemic conditions such as:

  • Alzheimer’s disease
  • Cardiovascular disease
  • Cystic fibrosis
  • Oral, esophageal, colorectal, pancreatic cancer
  • Inflammatory bowel disease (IBD)
  • Diabetes
  • Rheumatoid arthritis
  • Adverse pregnancy outcome
  • Respiratory tract infection

This growing body of research reveals a powerful truth: oral health is deeply connected to overall systemic well-being. 

Our Diagnostic Platform

Bridging the Gap in Oral Health Diagnostics

With decades of experience in oral health, clinical diagnostics, and molecular biology, we recognized gaps between labs, clinicians, and patients. Our end-to-end platform empowers timely, actionable insights:

  • UniquePerioSignature™ Panel – Test key periodontal pathogens
  • SalivaPreserv™ – Safe, easy saliva collection device
  • Cloud-Based LIMS – Clear, actionable reports
  • AI-Powered Treatment Recommendations – Based on latest research & ADA guidelines

 

 

The first-line treatment for periodontal disease often involves antibiotics. However, antibiotics do not differentiate between beneficial and harmful bacteria, leading to a significant reduction in both beneficial and harmful bacteria once treatment is completed. To help maintain low levels of oral pathogens while supporting the growth of beneficial bacteria, we also offer uniquely formulated oral and gut probiotics. Our formulation combines probiotics, prebiotics, and postbiotics—enhanced with nitric oxide precursors—to restore balance to the oral and gut microbiome, support long-term health, and strengthen resilience against oral microbiome dysbiosis.

Oral Health Support

UniqueSmile™ – Oral Microbiome Support

UniqueSmile™ Probiotics is a science-driven blend of 12 probiotic strains, 2 targeted prebiotics, and potent postbiotics from 25 probiotic cultures. Designed to restore balance healthy oral microbiome, UniqueGut™ supports nitric oxide production for blood circulation.

 

Gut Health Support
UniqueGut™ – Digestive & Immune Wellness

Your gut hosts trillions of microbes that play a vital role in maintaining your health. They aid in digesting food, absorbing nutrients, supporting your immune system, and even influencing your mood. Research shows that the gut microbiome is closely linked to overall human health Maintaining a balanced gut promotes better digestion, stronger immunity, and overall well-being.

Your gut hosts trillions of microbes essential for digestion, nutrient absorption, immunity, and overall health. UniqueGut™ combines 17 probiotics, 2 prebiotics, postbiotics, digestive enzymes, and CoQ-10 for full-spectrum support. Acid-resistant capsules ensure the beneficial bacteria reach your gut.

 

 

Saliva Specimen Collection Device

Collect Smarter with SalivaPreserv™
Tired of messy, unreliable saliva collection kits?
SalivaPreserv™ from Unique BiosciencesTM makes sample collection easy, clean, and stable—anytime, anywhere.

  • Dried preservative for a wide range of temperature stability (-20 °C to 35 °C)
  • No cold chain needed
  • Perfect for oral pathogen qPCR testing without the need of DNA extraction
  • Trusted by professionals. Ready for research or diagnostics

Simplify your workflow with SalivaPreserv™ today!