ADVANCED PERIODONTAL SALIVA TESTING FOR DENTAL PRACTICES

Stop Guessing. 

Start Testing.

Know the your patient's pathogen profile. Support informed care.
UniquePerioSignature™ uses saliva-based qPCR technology to detect and quantify five targeted periodontal pathogens from a simple saliva sample. Receive quantitative results in as little as 2 business days to support clinical assessment and patient management.
CLINIC LOGIN & REGISTRATION
Clinical Decision Support
Dental_Practice_1366x1366_matched
DIRECT-TO-CONSUMER PERIODONTAL SALIVA TESTING

Know Your Periodontal 

Pathogen Profile.

Understand. Share. Make Informed Decisions.
Bad breath and gum irritation may be linked to changes in your oral microbiome. A simple saliva test detects and quantifies five targeted periodontal pathogens, providing quantitative microbial information you can share with your dental professional.
Order Your Panel
VIEW full details
Copy_of_Unique_Biosciences_webpage_9
DAILY ORAL PROBIOTIC FOR ORAL MICROBIOME SUPPORT

Supports Oral Wellness

Support Fresh Breath.

Supports Fresh Breath and Oral Wellness.
12 probiotic strains. 2 targeted prebiotics. Postbiotics from controlled fermentation. UniqueSmile™ supports your oral microbiome where it actually lives, not just on the surface.
Shop UniqueSmile®
VIEW Full details
Smile_674406bd-560c-4a7d-8898-9e796893f5f3
ADVANCED DAILY PROBIOTIC + DIGESTIVE SUPPORT

Daily Gut Wellness.

Naturally.

Complete Gut Wellness, Naturally.
17 probiotic strains. Digestive enzymes. CoQ-10. UniqueGut™ supports your microbiome from the inside out, delivered in an acid-resistant capsule built to survive the trip to your gut.
Shop UniqueGut™
VIEW Full details
Gut_Hero_Picture

CLIA-CERTIFIED LAB

ecom-no-replace-giUQCu3o7bst-ic

qPCR TECHNOLOGY

ecom-no-replace-giUQCu3o7bst-ic

RESULTS IN 2 BUSINESS DAYS

ecom-no-replace-giUQCu3o7bst-ic

COMPETITIVE PRICING

ecom-no-replace-giUQCu3o7bst-ic

Why Choose Us

ecom-no-replace-6lBy313zFPicon-aff1

Cost-Effective

High-precision testing, highly competitive pricing accessible for every practice and patient.
ecom-no-replace-pFnUqFiopPicon-aff3

qPCR Accuracy

Identifies and quantifies 5 key periodontal pathogens with quantitative bacterial load. No estimates, no guesswork.
ecom-no-replace-J3fOjsxc5bicon-aff2

2-Day Turnaround

Full clinical report in 2 business days. Act on results without disrupting your workflow.
ecom-no-replace-J3fOjsxc5bicon-aff2

AI-Assisted Clinical Support

Our platform provides clinicians with AI-Assisted Clinical Support optimized for individual patient profiles.
ecom-no-replace-u5nhiInn8cicon-aff4

CLIA- Certified

Testing performed in a CLIA-certified high-complexity laboratory.

Complete Care for Your Smile, From the Inside Out.

Our advanced three-step protocol combines microbial testing with products designed to support oral and gut wellness and your overall health. 

Periodontal health starts with understanding your oral microbiome. The UniquePerioSignature™ Panel uses qPCR technology to identify and quantify 5 key oral pathogens in your saliva, providing clear microbial insights to support your dental assessment.

Once you understand your oral microbiome, take the next step in supporting it. UniqueSmile™ delivers 12 carefully selected probiotic strains with 25 billion CFU to help support a balanced oral microbiome and promote daily oral wellness.

UniqueGut™ is a comprehensive probiotic formula with 17 probiotic strains, 50 billion CFU, digestive enzymes, CoQ-10, prebiotics, and postbiotics to support digestive health, gut microbiome balance, and overall wellness.

Disclaimer: Statements regarding dietary supplements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

FREE SHIPPING for Orders over $30

transport

FREE SHIPPING for Orders over $30

transport

FREE SHIPPING for Orders over $30

transport

Everything You Need At One Place.

From microbial testing to daily wellness support, an integrated oral health platform.

Direct-to-Consumer Periodontal Saliva Testing
14% Off
Add to Wishlist Browse Wishlist
Compare Compare products

Direct-to-Consumer Periodontal Saliva Testing

$99.00 USD $85.00 USD
Add To Cart
UniqueSmile® ProbioticsUniqueSmile® Probiotics
20% Off
Add to Wishlist Browse Wishlist
Compare Compare products

UniqueSmile® Probiotics

$29.90 USD $23.90 USD
Add To Cart
UniqueGut™ ProbioticsUniqueGut™ Probiotics
24% Off
Add to Wishlist Browse Wishlist
Compare Compare products

UniqueGut™ Probiotics

$32.90 USD $24.99 USD
Add To Cart

WHO WE ARE

The Mouth Knows More Than You Think.

Founded by scientists, physicians, dentists, and innovators. Unique Biosciences exists to close the gap between patients, providers, and diagnostics. We believe better health decisions begin with timely, meaningful information.

Our team works to turn complex science into thoughtful solutions that help people make more informed decisions.

We don't just run tests. We give people the answers they've been missing.
Learn More About Us WATCH MORE

CLIA-CERTIFIED · QPCR TECHNOLOGY

One Test. Five Answers.

The UniquePerioSignature™ Panel identifies and quantifies key oral pathogens associated with periodontal disease with results in 2 business days.

UniquePerioSignature periodontal pathogen testing kit

Using advanced qPCR technology, the UniquePerioSignature™ Panel detects and quantifies 5 key periodontal pathogens — Aa, Pg, Pi, Td, and Tf — giving clinicians a comprehensive microbial profile to support earlier intervention, more accurate diagnosis, and personalized treatment plans.

  • Quantifies 5 key pathogens

    Aa, Pg, Pi, Td, and Tf

  • Results in 2 business days

    Fast, reliable results to support clinical decisions.

CLINIC LOGIN & REGISTRATION CLINICAL DECISION SUPPORT