ADVANCED PERIODONTAL SALIVA TESTING FOR DENTAL PRACTICES

Stop Guessing. 

Start Testing.

Know the your patient's pathogen profile. Support informed care.
UniquePerioSignature™ uses saliva-based qPCR technology to detect and quantify five targeted periodontal pathogens from a simple saliva sample. Receive quantitative results in as little as 2 business days to support clinical assessment and patient management.
CLINIC LOGIN & REGISTRATION
Clinical Decision Support
Dental_Practice_1366x1366_matched
DIRECT-TO-CONSUMER PERIODONTAL SALIVA TESTING

Know Your Periodontal 

Pathogen Profile.

Understand. Share. Make Informed Decisions.
Bad breath and gum irritation may be linked to changes in your oral microbiome. A simple saliva test detects and quantifies five targeted periodontal pathogens, providing quantitative microbial information you can share with your dental professional.
Order Your Panel
VIEW full details
Copy_of_Unique_Biosciences_webpage_9
DAILY ORAL PROBIOTIC FOR ORAL MICROBIOME SUPPORT

Supports Oral Wellness

Support Fresh Breath.

Supports Fresh Breath and Oral Wellness.
12 probiotic strains. 2 targeted prebiotics. Postbiotics from controlled fermentation. UniqueSmile™ supports your oral microbiome where it actually lives, not just on the surface.
Shop UniqueSmile®
VIEW Full details
Smile_674406bd-560c-4a7d-8898-9e796893f5f3
ADVANCED DAILY PROBIOTIC + DIGESTIVE SUPPORT

Daily Gut Wellness.

Naturally.

Complete Gut Wellness, Naturally.
17 probiotic strains. Digestive enzymes. CoQ-10. UniqueGut™ supports your microbiome from the inside out, delivered in an acid-resistant capsule built to survive the trip to your gut.
Shop UniqueGut™
VIEW Full details
Gut_Hero_Picture

CLIA-CERTIFIED LAB

ecom-no-replace-giUQCu3o7bst-ic

qPCR TECHNOLOGY

ecom-no-replace-giUQCu3o7bst-ic

RESULTS IN 2 BUSINESS DAYS

ecom-no-replace-giUQCu3o7bst-ic

COMPETITIVE PRICING

ecom-no-replace-giUQCu3o7bst-ic

SCIENCE-DRIVEN HEALTH INSIGHTS

Making complex science more meaningful for better health.

Unique Biosciences brings advanced testing technology and scientific insights together to support a deeper understanding of oral and overall health.

FOR DENTAL PROFESSIONALS

Bring Microbial Insights Into Your Practice.

Detect and quantify five periodontal pathogens with UniquePerioSignature™ saliva-based qPCR testing.

Quantitative Results
CLIA Certified Laboratory
Reports for Clinical Support
In-Office Saliva Test

FOR INDIVIDUALS

Understand Your Oral Microbiome.

Collect a saliva sample at home and discover insights into your oral health with our convenient Home Saliva Test.

Learn About Your Oral Health
Support Daily Oral Wellness
Explore Gut Health Solutions
Home Saliva Test
Science-Based Solutions
CLIA Certified Laboratory
Trusted by Dental Professionals
Supporting Oral & Gut Health

CLIA-CERTIFIED LABORATORY · MULTIPLEX qPCR

One Saliva Sample. Five Targeted Pathogens. Clearer Insights.

UniquePerioSignature™ uses multiplex qPCR technology to detect and quantify five targeted periodontal pathogens from a simple saliva sample. Results are available in as little as two business days.

UniquePerioSignature periodontal pathogen testing kit

The panel measures five targeted periodontal pathogens - Aa, Pg, Pi, Td, and Tf - to provide a quantitative microbial profile that can support clinical assessment and informed discussions with patients. Results should be considered alongside clinical findings and professional judgment.

  • Quantifies five targeted pathogens

    Aa, Pg, Pi, Td, and Tf

  • Results in as little as 2 business days

    Quantitative laboratory results to inform clinical discussions.

  • Multiplex qPCR technology

    Detects and quantifies multiple targeted pathogens in one test.

  • Supports clinical assessment

    Adds microbial data to the broader clinical picture.

CLINICAL DECISION SUPPORT CLINIC LOGIN & REGISTRATION

Complete Care for Your Smile, From the Inside Out.

Our advanced three-step protocol combines microbial testing with products designed to support oral and gut wellness and your overall health. 

Periodontal health starts with understanding your oral microbiome. The UniquePerioSignature™ Panel uses quantitative polymerase chain reaction (qPCR) technology to detect and measure five targeted periodontal pathogens in a saliva sample. The laboratory report provides quantitative information about the microorganisms detected, helping you and your dental professional better understand your oral microbial profile. These results can be considered alongside a clinical examination, dental history, and other relevant findings to support informed discussions about periodontal health and care.

Once you understand your oral microbiome, take the next step in supporting it. UniqueSmile™ combines 12 carefully selected probiotic strains, delivering 25 billion CFU per serving, with targeted prebiotics and bioactive postbiotics. This formulation is designed to support a balanced oral microbiome and promote daily oral wellness as part of your regular oral care routine. With 30 convenient stick packs per box, UniqueSmile™ makes it easy to incorporate probiotic supplementation into your daily routine, alongside brushing, flossing, and regular dental checkups.

A balanced gut microbiome is an important part of digestive wellness. UniqueGut™ combines 17 probiotic strains, delivering 50 billion CFU, with digestive enzymes, CoQ-10, prebiotics, and postbiotics in one comprehensive formula. Designed to support digestive health, gut microbiome balance, and overall wellness, this multi-component formulation brings together probiotics and complementary ingredients in a convenient daily supplement. UniqueGut™ can be incorporated into a balanced lifestyle alongside a varied diet and healthy daily habits.

Disclaimer: Statements regarding dietary supplements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

Our Probiotic Solutions

Daily Support for a Healthier You

Explore our probiotic formulations for oral and digestive wellness.

Oral Health

UniqueSmile® Probiotics

A daily probiotic supplement formulated to support oral microbiome balance and fresh breath.

25 billion CFU

12 targeted probiotic strains

Convenient stick packs

30 individual servings

Supports oral health

Helps maintain a healthy oral microbiome

Shop UniqueSmile® Learn More

Digestive Health

UniqueGut™ Probiotics

A comprehensive probiotic formulation to support digestive health and overall gut wellness.

17 probiotic strains

With targeted prebiotics and postbiotic components

Digestive enzymes and CoQ10

Additional components for daily support

Enteric-coated capsules

60 capsules per bottle

Shop UniqueGut™ Learn More

FREE SHIPPING 

transport

FREE SHIPPING 

transport

FREE SHIPPING 

transport

Everything You Need At One Place.

From microbial testing to daily wellness support, an integrated oral health platform.

Direct-to-Consumer Periodontal Saliva Testing
14% Off
Add to Wishlist Browse Wishlist
Compare Compare products

Direct-to-Consumer Periodontal Saliva Testing

$99.00 USD $85.00 USD
Add To Cart
UniqueSmile® ProbioticsUniqueSmile® Probiotics
20% Off
Add to Wishlist Browse Wishlist
Compare Compare products

UniqueSmile® Probiotics

$29.90 USD $23.90 USD
Add To Cart
UniqueGut™ ProbioticsUniqueGut™ Probiotics
24% Off
Add to Wishlist Browse Wishlist
Compare Compare products

UniqueGut™ Probiotics

$32.90 USD $24.99 USD
Add To Cart

WHO WE ARE

The Mouth Knows More Than You Think.

Founded by scientists, physicians, dentists, and innovators. Unique Biosciences exists to close the gap between patients, providers, and diagnostics. We believe better health decisions begin with timely, meaningful information.

Our team works to turn complex science into thoughtful solutions that help people make more informed decisions.

We don't just run tests. We give people the answers they've been missing.
Learn More About Us WATCH MORE